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KMID : 0364219700130010029
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Korean Journal of Zoology
1970 Volume.13 No. 1 p.29 ~ p.33
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Chromosome Studies on the Cultured Uterine Carcinoma Cells
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Kang Yung-Sun
Kim Suk-Whan
Lee Chung-Keel
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Abstract
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The conclusions established in the present study on the chromosomes in vitro of the uterine carcinomas of Korean women are as follows: 1. The pattern of the distribution of chromosome number in uterine carcinoma cells was quite different from that of normal cells, and modal number of the chromosome was 45 and 46. 2. The frequency of diplochromosomes was 0.053 per cell (5.3%) and that of chromosome aberration was 0.16 per cell (16%), which are significantly higher than each of normal cells. In chromosome aberration types, chromatid and isochromatid deletions (chromatid type) and dicentric (chromosome type) were observed. 3. Idiogram analysis showed a tendency that the number of chromosomes belonging to group F increased while that of chromosomes in groups B and E decreased in total. The number of chromosomes in groups C and G in the hypodiploidy cells decreased, but it increased in the hyperdiploidy cells.
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